A MiFLOW clinical trial
Advanced Imaging for the Assessment of Lower Urinary Tract Symptoms
This study optimizes novel imaging methods in healthy volunteers and patients with LUTS.
- Study type
- Observational Pilot Study
- Where
- University of Michigan, University of Wisconsin
- Funding
- Sponsor or funder
- Registry
- NCT number
About the trial
Changing the Way we Image LUTS
The overall goal is to develop and validate advanced imaging techniques for the characterization of LUTS. We will develop strategies for early diagnosis and intervention that facilitate development of effective medical options to prevent progression to end-stage bladder dysfunction.
Use advanced MR and US imaging techniques to evaluate the anatomy, function and viscoelastic properties of the prostate in men.
Perform dynamic imaging techniques, including MRI and ultrasound to characterize wall motion coordination, symmetry and calculated efficiency of the detrusor contraction, bladder base, bladder neck, urethra, and other metrics that define voiding and micturition.
Use imaging techniques (MR, US, CT) to quantify metabolic health.
Understand the relationship of imaging and clinical variables.
What taking part involves
- Up to 3 research visits
- Participation involves: An MRI, a rectal ultrasound, or both along with brief surveys
- Compensation is available, upwards of $300.
Recruitment
Our recruitment goal
Symptomatic Participants
50 Healthy Volunteers
Who can take part
Eligibility
The study team makes the final decision about who can take part. Taking part is always voluntary.
Inclusion- Patients
- Men, age 18-85
- Symptoms consistent with LUTS
- No Contraindications to MRI (e.g pacemaker, contraindicated metallic implants, claustrophobia, etc)
- No history of prior prostate surgery or pelvic radiation
Inclusion- Volunteers
- Men, 18-85
- No symptoms consistent with LUTS
- No Contraindications to MRI (e.g pacemaker, contraindicated metallic implants, claustrophobia, etc)
- No history of prior prostate surgery or pelvic radiation
Patients with severe renal/kidney disease or allergy to gadolinium based contrast will not have contrast.
Interested in taking part?
Contact the study team to learn more.
Please note that all emails and voicemails will receive a response within 48 business hours.